Ochratoxin A and Mitotic Disruption: Mode of Action Analysis of Renal Tumor Formation by Ochratoxin A
نویسندگان
چکیده
منابع مشابه
Ochratoxin A-induced tumor formation: is there a role of reactive ochratoxin A metabolites?
Ochratoxin A is a nephrotoxic and tumorigenic mycotoxin which contaminates a variety of food items, resulting in chronic human exposure. Biotransformation reactions have been implicated in the tumorigenicity of ochratoxin A. The biotransformation of ochratoxin A by cytochromes P450 and other mammalian enzymes was investigated to optimize conditions for bacterial mutagenicity testing. Metabolite...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2012
ISSN: 1096-0929,1096-6080
DOI: 10.1093/toxsci/kfs105